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Cellometer® Automatic Cell Counters - Advantages

  • Simple & fast
  • Morphology observation
  • Small footprint and affordable
  • No washing and clogging and cross-contamination
  • No hardware change between large or small cell sizes
  • One sample, all data produced with the same measurement


Compare to hemacytometer
Compare to particle and fluorescence counters
Compare to other imaging cell counter

 

Compare to hemacytometer

 

Auto T4

Hemacytometer

Principle 1

Same

Cell suspension in a thin layer

Principle 2

Same

Microscopy

Counting operation

Automatic

Manual

Viability

Same

Trypan blue

# of cells

100 to >4000

100-300

Save data

Yes

No

Save image

Yes

No

Cell size

Yes

Only visual

Distinguish
by cell size

Yes

Very hard

Operator dependency

None

Very large

Washing

No

Yes

Time saving

~ 500%

N/A



Compare to particle and fluorescence counters

 

Auto T4

Particle counter

Fluorescence counter

Cell morphology

Yes

No

No

Visual verification

Yes

No

No

Viability

Yes

No

Yes

Cell size

Yes

Yes

No

Save data

Yes

 

Yes

Save image

Yes

No

No

Special reagent

No

Yes

Yes

Potential clogging

No

Yes

Yes

Washing

No

Yes

Yes

Potential contamination

No

Yes

Yes

Operation

Simplest

OK

Complicated

Counting time

Fast

OK

Longer

Routine calibration

No

Yes

Yes

Instrument size

Smallest footprint

Larger

larger

Cost

Lowest

More

Much more



Compare to other imaging cell counter

 

Auto T4

Other imaging-based counters

Sample volume

20 micro-liter

> 300 micro-liter

Counting time

< 30 sec.
for typical count

Much longer

Special reagent

No

Yes

Potential clogging

No

Yes

Washing

No

Yes

Potential contamination

No

Yes

Operation

Simplest

OK

Counting time

Fast

OK

Routine calibration

No

Yes

Instrument size

Smallest footprint

Larger

Cost

Lowest

Much, much more