A Novel NK Cell-Mediated Cytotoxicity Detection Method Using the Cellometer Vision

It’s White Paper Wednesday! Read our featured white paper: A Novel NK Cell-Mediated Cytotoxicity Detection Method Using the Cellometer Vision

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As part of the innate immune system, natural killer (NK) cells are the primary form of defense against tumor cells and assorted pathogens [1]. A minor subset of NK cells (CD56brightCD16-) influence immune regulation via the secretion of cytokines interferon-γ and TNF-α [2]. The major subset of NK cells (CD56dimCD16+), however, directly lyse their targets [3]. Consequently, understanding the cytolytic functions of NK cells are key to understanding NK cell biology and function in adoptive immunotherapy.

 

 

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By |2016-03-02T10:00:54+00:00March 2nd, 2016|Categories: Cellometer Application News|Tags: , , |0 Comments

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