Innovative Cytotoxicity Assays Utilizing Imaging Cytometry to Investigate Anti-Tumor Immunity
The ongoing pursuit of novel anti-cancer therapeutics must consider the potential for off-target effects on the immune system.
The ongoing pursuit of novel anti-cancer therapeutics must consider the potential for off-target effects on the immune system.
The researchers in this study first utilized various techniques to explore the role of MEX3A in glioma, including immunohistochemistry to assess MEX3A expression levels in glioma tissues, knockdowns of MEX3A in conjunction with a transwell assay to assess migration and an in-vivo mouse model of tumor burden.
The severe acute respiratory coronavirus 2 (SARS-CoV-2) has caused the ongoing COVID-19 pandemic, infecting more than 206 million people and causing upwards of 4.34 million deaths at the time of writing.
Metastatic spreading from solid tumors continues to be one of the greatest challenges facing oncologists and clinicians, often leading to a fatal outcome for many patients.
Perform simultaneous imaging and analysis to rapidly capture and quantify spheroid images in every well with advanced software segmentation.
Researchers highlight the need for large-scale screening of cytotoxic cells and their ability to kill target cell lines in both a 2D and 3D fashion.
Virology researchers use CPE effects pathogens elicit on the host to study host-pathogen interactions.
The COVID-19 pandemic has increased SARS-CoV-2 research globally resulting in three publicly available vaccines from Moderna, Pfizer (mRNA-based), and Johnson & Johnson (viral vector-based).
Monoclonal cell culture is critical for many research areas however, the process to establish monoclonal cell lines is time-consuming, and many methods used to monitor monoclonality of cell culture still rely on manual and low-throughput methods.
Effective long-term cryopreservation of human mesenchymal stem cells is an essential component of regenerative medicine and tissue engineering applications.