Video Workflow-at-a-Glance: NK Cell-Mediated Cytotoxicity Assay
Directly image and count calcein AM-labeled target cells in a 96-well plate using Celigo image cytometer. Concurrent imaging and analysis in 8 minutes.
Video Workflow-at-a-Glance: Seahorse™ Normalization Assay
Celigo Image Cytometer provides a fast, effective, and cell stress-free technique to count cells plated onto uncoated or coated culture plates.
Normalizing Seahorse™ XF Data with Label-Free Cell Counting
How to use Celigo image cytometry to normalize Seahorse™ XF data and eliminate time-consuming protein-based process.
Evaluating Anticancer Drug Compounds using Image Cytometry
Image-based, automated analysis of 3-D tumor spheroids in microwell plates is becoming standard practice for the evaluation of anticancer drug compounds.
Automated Cell Counters: Accurate, Reproducible Cell Counts for the Entire Cell Therapy Workflow
Cellometer automated cell counters have been facilitating CAR T manufacturing with accurate cell counting and analysis since 2010.
Celigo Provides Image-Based Proof of Single-Cell Clonality
The FDA identifies clonality as one of the most crucial steps in guaranteeing cell line quality and safety. The Celigo Image Cytometer makes single cell sorting easy.
Poster: High-throughput immune complex analysis method for CAR T cell-mediated cytotoxicity using the Celigo Image Cytometer
Download our Poster Abstract: Cancer immunotherapy has been gaining momentum in the field of cancer research. Specifically, Chimeric Antigen Receptor (CAR) T cell technology have introduced new methods to combat cancer. Direct cell-mediated cytotoxicity assays are required to assess the killing capability of the engineered CAR T cells. Traditionally, these assays are conducted by measuring the amount of released Chromium, calcein AM, or LDH molecules after the target cancer cells are killed with CAR T cells. These methods require a large amount of target cells which may not be ideal when working with donor primary samples. Additionally, they cannot [...]
High throughput, high-resolution image acquisition for DNA damage detection
Celigo playing an important role in high throughput, high-resolution image acquisition for DNA damage detection. The Celigo S captures 16 images of each well that are then stitched into a single representation Open access article: Next generation high throughput DNA damage detection platform for genotoxic compound screening
Benefits of direct high-throughput cell counting in immuno-oncology research
By directly imaging and counting every cell in a well over a course of a drug treatment, the Celigo can perform the cytotoxicity assays in a label-free format.
Celigo 5 Channel system officially released
Lawrence, Massachusetts – September, 2016 - Nexcelom Bioscience, a leading provider of cell counting and analysis products for biomedical research and the biopharma industry, announced it has released the addition of a 5th channel available as an option on the Celigo image cytometer. The Celigo is a bench-top image cytometry system providing whole-well imaging and quantitative data, through image analysis for demanding cell-based analytical applications. Previous configurations allowed bright field only imaging, or bright field imaging plus 3 fluorescent channels. This new option of bright field plus 4 fluorescent (red, green, blue and far-red) channels will allow researchers more capabilities [...]