ViaStain™ CFSE
CS1-P0002-1
Nexcelom ViaStain™ CFSE is a cell-permeable, non-fluorescent compound. Upon crossing the cell membrane, CFSE is rapidly hydrolyzed by cellular esterases inside live cells converting it from a non-fluorescent to a strongly green fluorescing dye. CFSE then covalently binds to intracellular proteins, making it a good candidate for multi-day cell labeling. Upon cell division, approximately half of the fluorescent label is passed onto the daughter cell. After each successive cell division, the fluorescent intensity of the dye is reduced by half and the staining appears proportionately dimmer. The dye becomes difficult to detect after approximately 3-5 generations.
For additional documentation, please contact support at support@nexcelom.com
Learn more about Proliferation/Tracer Reagents