Measuring Drug Effect on Cell Cycle Profile Using the Cellometer Vision Image Cytometer
Cell cycle analysis is a commonly used assay in both clinical diagnosis and biomedical research. This analysis distinguishes cells in different phases of cell cycle and is often used to determine cellular response to drugs and biological stimulations [1, 2]. Because this assay is based on measuring the DNA content in a cell population, it can also be used to analyze DNA fragmentation during apoptosis, requiring multicolor fluorescent staining of biomarkers and DNA [3].