Nexcelom’s CTO on the Future of CAR T Workflow

Nexcelom Bioscience is a pioneer in the field of cell counting and cell-based assays since 2003. We work with cell therapy researchers to ensure Precision, Linearity, Accuracy, and Reproducibility of data. In this interview, Dr. Jean Qiu, our founder, and CTO, describes 3 major reasons why we partner with global and local research organizations to streamline CAR T workflow.
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The CAR T Cell Revolution

Cancer immunotherapy has been revolutionized by the discovery and development of chimeric antigen receptors (CAR) T cells. CAR T cells are defined as genetically engineered allogeneic T cells that are isolated from blood, developed in the laboratory using viral vectors, and then infused into a patient to fight cancer cells. CAR T cell therapy is type of immunotherapy that has already received two FDA approvals for tisagenlecleucel (Kymriah) from Novartis and Axicabtagene ciloleucel (Yescarta) from Kite Pharma/Gilead. Researchers will soon break ground on how to use CARs for solid tumors.

Accurate Cell Counting Matters

A common thread that unifies researchers and regulators is the importance of immune cell quality in the CAR-T workflow. Ensuring accurate and consistent cell counts, viability, and functionality (e.g. CAR-T cytotoxicity) is why most premier research organizations choose Nexcelom cell counters and image cytometers.

By |2019-01-15T20:49:37+00:00January 15th, 2019|Categories: Accurate Cell Counting, Latest News|Tags: , , , , |0 Comments

About the Author:

Leo Chan
Dr Leo Chan currently serves as the Technology R&D Manager at Nexcelom Bioscience LLC, Lawrence, MA. His research involves in the development of instrument and applications for the Celigo and Cellometer image cytometry system for detection and analysis of cells for oncology and immunology research. He is a member of the American Association of Cancer Research and the American Association of Immunologists. He received his B.S., M.S., and Ph.D. in Electrical and Computer Engineering from the University of Illinois at Urbana-Champaign (2000-2008).

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