ViaStain™ Total ROS Green
Oxidative stress is caused by an accumulation of reactive oxygen species (ROS) within cells or tissues. While the production of ROS is part of the normal cellular metabolic processes, the cell’s inability to neutralize these radicals may have a direct impact on cell health, physiological functions, and possibly lead to cell damage or even cell death. Over the years, oxidative stress has been linked with multiple chronic and degenerative diseases such as cardiovascular disease, diabetes, osteoporosis, stroke, inflammatory diseases, neurodegenerative diseases, and cancer. The role of antioxidants, including vitamins C and E, polyphenols, and flavonoids, in the reduction of oxidative stress, continues to be a major area of study.
ViaStain™ Total ROS Green kits for Cellometer Spectrum and Cellaca MX uses a unique ROS sensor to quantify ROS in live cells. ROS Green is a cell-permeable stain that generates a strong green fluorescence signal upon reaction with ROS to obtain quantitative cell metrics.