ELISpot is an assay for the detection and enumeration of cytokine secreting cells. Accurate cell counting is important for ELISpot.
The use of modern automation has largely eliminated many of the hemacytometer's sources of error, increasing the accuracy and efficiency of cell counting today.
Everyone I meet that performs primary cell counting wants to optimize the amount of time they spend doing that task. They also agree that 30 seconds per count sounds pretty good.
Cellometer automated cell counters have been facilitating CAR T manufacturing with accurate cell counting and analysis since 2010.
Tired of manual cell counting? Let's face it, manual cell counting is tedious. When your day is filled with culturing many cell lines at one time, that's hours of your day just to get the data you need. Not only that, the manual process can be riddled with judgment errors, miscounts, and user-to-user variability. I know what you’re thinking, "You're telling me my hours hunched over a microscope counting cells may not even be producing reliable data?!" Yup. You need a superhero. "So what are my options?" Well, what if there were a powerful superhero that could take a small [...]
As the first automated cell counter ever manufactured, the Auto T4 set the standard with its pattern-recognition software and bright field imaging used to calculate cell count, concentration and viability with Trypan Blue.
STEM - Science, Technology, Engineering and Mathematics - is vital to our future. At present, our students are not stacking up with the other developed countries. We understand the value and importance of encouraging students to explore these STEM fields, and consider a career in a STEM. For that reason, we created a package specifically designed with high schools, colleges and universities in mind. It's called our Teaching Lab - and it has everything a teacher needs to bring automated cell counting technology into their classrooms and labs at a discounted price. The Cellometer Mini and Cellometer Auto 1000 are [...]
Our founder, Dr. Jean Qiu, developed the Cellometer Auto T4 in 2005 after receiving a request for such an instrument from a customer at NIH, and we officially launched it at AACR 2006. As we come up on the 10 year anniversary of the original launch of our first automated cell counter it got us thinking. When we created the first automated cell counter, we created the market for such devices and we were alone in the equipment space for 2-3 years before any other company came out with competitive products. (Imitation is the highest form of flattery, right?) It was [...]
The University of Kentucky investigated progesterone receptor membrane component 1 (PGRMC1), an often upregulated component in thyroid, breast, colon and lung tumors. PGRMC1 has been associated with drug resistance and is thought of as an indicator of prognosis. The researchers employed a variety of cell types to represent head and neck cancers, as well as oral, lung and ovarian cancers. These cells were exposed to PGRMC1 inhibitors. The Cellometer performed cell counts with Trypan Blue. The PGRMC1 inhibitors successfully prompted cancer stem cell death even when other anti-cancer agents did not. The researchers suggest using PGRMC1 as a cancer stem [...]
Researchers at the University of Manchester (UK) created a reference database of 1,800 quantified S. cerevisiae proteins via specific isotope labeling and mass spectrometry. This is the largest database of its kind created to date, and the goal was to obtain a better understanding of intracellular protein concentrations, important information for those involved in molecular systems biology. The Cellometer was used to maintain accurate cell counts throughout experimentation. This database can now serve as a standard for the yeast proteome in all research going forward. Read the full publication here. The Cellometer automated cell counters can provide many advantages in [...]