Designing high-content tumor spheroid drug screening using high-throughput image cytometry

Solid tumor biology has become a critical step in accessing the potency of many cancer drugs. 3D spheroids and organoids can provide measurements such as size differences under drug conditions or metabolism and diffusion rates critical to drug development.

A rapid method to establish potential molecular targets for colorectal cancer progression

The development of targeted molecular therapies is an increasingly popular approach to combat and overcome the limitations of conventional treatments.

Identifying Downstream Candidates for Targeted Molecular Therapy

A fundamental understanding of the molecular mechanisms responsible for the development and progression of RCC will be pivotal in developing next-generation treatment protocols to improve patient outcomes.

Cell counting: A practical guide to evaluating cell counting methods

Because there is no certified reference material to determine cell concentration, ISO cell counting standards are a valuable tool for evaluating and selecting fit-for-purpose cell counting methods.

Innovative Cytotoxicity Assays Utilizing Imaging Cytometry to Investigate Anti-Tumor Immunity

The ongoing pursuit of novel anti-cancer therapeutics must consider the potential for off-target effects on the immune system.

High-Throughput Imaging Cytometry for Rapid Investigation in the Role of MEX3A in Glioma

The researchers in this study first utilized various techniques to explore the role of MEX3A in glioma, including immunohistochemistry to assess MEX3A expression levels in glioma tissues, knockdowns of MEX3A in conjunction with a transwell assay to assess migration and an in-vivo mouse model of tumor burden.

By |2022-01-19T19:38:13+00:00January 19th, 2022|Categories: Celigo, Latest News, Neurology|Tags: , , , |0 Comments

High-Throughput Imaging Assessing Virus-Neutralizing Activity of Sera from Vaccinated Individuals

The severe acute respiratory coronavirus 2 (SARS-CoV-2) has caused the ongoing COVID-19 pandemic, infecting more than 206 million people and causing upwards of 4.34 million deaths at the time of writing.

Celigo Continues to be a Valuable Tool for 3D Immunotherapy Models

Metastatic spreading from solid tumors continues to be one of the greatest challenges facing oncologists and clinicians, often leading to a fatal outcome for many patients.

By |2022-01-31T21:34:42+00:00September 20th, 2021|Categories: 3D Models, Latest News|Tags: , , , |0 Comments

Is your 2D assay giving superficial information?

Perform simultaneous imaging and analysis to rapidly capture and quantify spheroid images in every well with advanced software segmentation.

Establishing a High-throughput Screening Platform for NK mediated Cytotoxicity using Image Cytometry

Researchers highlight the need for large-scale screening of cytotoxic cells and their ability to kill target cell lines in both a 2D and 3D fashion.

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