During this webinar we highlight a variety of assays to support the development of cell therapies for solid tumors. We review:
- Challenges in cell therapy development targeting solid tumor
- T cell activation, proliferation and T cell mediated killing assays
- Personalized organoid models for T cell mediated cytotoxicity
- Co-culture assay to measure specificity of immunotherapies
We introduce image cytometry and how it has enabled the development and characterization of T cell therapies. We highlight novel in vitro models, including the use of patient-derived organoid to evaluate T cell efficacy, and co-culture of target and non-target cells to measure specificity of immunotherapies.
Speaker: Andrea C. Love, PhD
Andrea received her PhD in Immunology and Microbiology from New York Medical College. Her research focused on immune cell signaling and activation in the context of infectious disease, with particular emphasis on differential host-pathogen interactions. She joined Nexcelom in 2014 as a Field Applications Scientist, and currently serves as a Senior Business Development Manager, providing subject-matter expertise in the immunology and immuno-oncology research areas.