This webinar highlights a variety of assays to support the development of cell therapies for solid tumors. We will review:
- Challenges in cell therapy development targeting solid tumor
- T cell activation, proliferation and T cell mediated killing assays
- Personalized organoid models for T cell mediated cytotoxicity
- Co-culture assay to measure specificity of immunotherapies
We will introduce image cytometry and how it has enabled the development and characterization of T cell therapies. We will highlight novel in vitro models, including the use of patient-derived organoid to evaluate T cell efficacy, and co-culture of target and non-target cells to measure specificity of immunotherapies.