How to Improve your Primary Cell Analysis: Make it Accurate, Quick and Simple
This webinar takes a look at primary cell analysis and the difficulties of counting with traditional methods and presents an alternative of fluorescent counting.
How to Perform High Throughput Cell Cycle Assays
This webinar takes a look cell cycle. How is it currently examined? Is there a better way? What if cell cycle assays could be performed in a high throughput method?
How to Measure Yeast Cell Concentration and Viability in Corn Mash
This video demonstration features the Cellometer Vision to measure yeast cell concentration and viability in a highly viscous corn mash sample.
How to Measure Live Cell Concentration and Viability of Human PBMC
This video demonstration features the Cellometer Vision to measure live cell concentration and viability of human PBMC.
How to use Image Cytometry to Accurately Analyze Primary Hepatocytes
This video will show you how to use bright field and dual-fluorescence imaging to accurately analyze live and dead primary hepatocytes in heterogeneous samples.
Novel Fluorescent Viability and Vitality Detection Method for Ale and Lager Yeast Fermentation using Cellometer Vision
It's White Paper Wednesday! Read our featured white paper: Novel Fluorescent Viability and Vitality Detection Method for Ale and Lager Yeast Fermentation using Cellometer Vision Automated cell counting methods can monitor yeast concentration and viability throughout fermentation to ascertain cell health and the amount of yeast to be pitched or repitched, all of which contributes to the quality and flavor consistency of the final product [1,2,3]. Analyzing physiological and metabolic characteristics of the yeast cells permits operators to efficiently monitor yeast viability and vitality for quality control purposes, which impacts long-term storage and other physiological stresses. Download our white [...]
A Novel NK Cell-Mediated Cytotoxicity Detection Method Using the Cellometer Vision
It's White Paper Wednesday! Read our featured white paper: A Novel NK Cell-Mediated Cytotoxicity Detection Method Using the Cellometer Vision As part of the innate immune system, natural killer (NK) cells are the primary form of defense against tumor cells and assorted pathogens [1]. A minor subset of NK cells (CD56brightCD16-) influence immune regulation via the secretion of cytokines interferon-γ and TNF-α [2]. The major subset of NK cells (CD56dimCD16+), however, directly lyse their targets [3]. Consequently, understanding the cytolytic functions of NK cells are key to understanding NK cell biology and function in adoptive immunotherapy. Download our white [...]
Cellometer Vision helps undergraduates explore immunophenotyping in mouse bone marrow stem cells
A collaboration between Merrimack College (North Andover, MA) and Nexcelom Bioscience LLC used a Cellometer Vision in an undergraduate immunology classroom to explore differentiation, activation, cell surface marker expression and cytokine production in mouse bone marrow stem cells. The Cellometer Vision allowed the students to visualize and analyze their cells for various surface markers before designing experiments to explore the activity of natural anti-inflammatory compounds on TNF-alpha production. Read the full publication here. More than 50% of Nexcelom employees hold advanced degrees - so it's no surprise that we love collaborations with other scientists and institutions. Many of our academic [...]
Trypan Blue and Fluorescence-Based Viability Detection Methods Via Morphological Observation
Over a time course analysis in standard cell culture, TB exclusion reports more viability in comparison to the fluorescence-based tools
Cellometer Vision is used to characterize fungi suitable for pest management
Entomopathogenic fungi (ENPF)– those fungal species that use insect hosts to propagate – are of note in India due to their potential utility in pest management. The Indian Institute of Technology (New Delhi, India) obtained soil samples and isolated ENPF with the intention of studying how these types of fungi might be used to control the house fly, Musca domestica, an insect that causes many health problems in humans and animals in that country. The samples were then characterized molecularly and tested for pathogenicity against M. domestica. The Cellometer Vision was used to accurately maintain spore counts. Through this work, [...]