Repurposing immune cells to develop new therapies

For the development of new drugs and the advancement of new cell therapies, pharmaceutical companies have recurred to cytotoxicity assays as a quick way to assess the viability of cell lines in response to an external stimulus.

Webinar on Demand: Cell Counting Method Development for CAR-T Cell Therapy

Webinar on Demand: Accurate and consistent cell counting methods for development and manufacturing of CAR-T under GMP/GLP conditions.

Nexcelom’s CTO on the Future of CAR T Workflow

Nexcelom founder and CTO, Dr. Jean Qiu, describes 3 major reasons why we partner with global and local research organizations to streamline CAR-T workflow.

Automated Cell Counters: Accurate, Reproducible Cell Counts for the Entire Cell Therapy Workflow

Cellometer automated cell counters have been facilitating CAR T manufacturing with accurate cell counting and analysis since 2010.

Poster: High-throughput immune complex analysis method for CAR T cell-mediated cytotoxicity using the Celigo Image Cytometer

Download our Poster Abstract: Cancer immunotherapy has been gaining momentum in the field of cancer research. Specifically, Chimeric Antigen Receptor (CAR) T cell technology have introduced new methods to combat cancer. Direct cell-mediated cytotoxicity assays are required to assess the killing capability of the engineered CAR T cells. Traditionally, these assays are conducted by measuring the amount of released Chromium, calcein AM, or LDH molecules after the target cancer cells are killed with CAR T cells. These methods require a large amount of target cells which may not be ideal when working with donor primary samples. Additionally, they cannot [...]

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