With new variants and waning immunity occurring, especially in elderly and immunocompromised individuals, it is important to understand how to utilize the tools we have to prevent severe disease and death.
The Celigo Image Cytometer has been previously used for a wide range of immuno-oncology and immunotherapy studies, demonstrating the great utility of this instrument to assess the activity of cytotoxic immune cells against malignant cells of interest.
Sangivamycin is an unsuccessful anti-cancer drug candidate that has proven to be a potent inhibitor of multiple viruses. The authors of this study hypothesized that this compound would also be active against SARS-CoV-2.
Image cytometry for cell counting, proliferation, cell cycle, and other assays for whole-well live-cell analysis and cell sample characterization in brightfield and fluorescence.
Establishing a High-throughput Screening Platform for NK mediated Cytotoxicity using Image Cytometry
Researchers highlight the need for large-scale screening of cytotoxic cells and their ability to kill target cell lines in both a 2D and 3D fashion.
Taking Advantage of Viral Cytopathic Effects to Aid in the Rapid Screening of Effective Viral Therapies
Virology researchers use CPE effects pathogens elicit on the host to study host-pathogen interactions.
The COVID-19 pandemic has increased SARS-CoV-2 research globally resulting in three publicly available vaccines from Moderna, Pfizer (mRNA-based), and Johnson & Johnson (viral vector-based).
Effective long-term cryopreservation of human mesenchymal stem cells is an essential component of regenerative medicine and tissue engineering applications.
Detection of novel CD276-CAR NK-92 mediated cytotoxicity of neuroblastoma tumor spheroids using plate-based image cytometry
Drug repurposing, also known as drug repositioning is a powerful tool for the rapid expansion of available therapy options by identifying new therapeutic uses from pre-existing drugs.